A carregar...
Design, synthesis and biological evaluation of benzimidazole–rhodanine conjugates as potent topoisomerase II inhibitors
In this study, a series of benzimidazole–rhodanine conjugates were designed, synthesized and investigated for their topoisomerase II (Topo II) inhibitory and cytotoxic activities. The results from Topo II-mediated pBR322 DNA relaxation and cleavage assays showed that the synthesized compounds might...
Na minha lista:
| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072309/ https://ncbi.nlm.nih.gov/pubmed/30109008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00278a |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|