Desketoneoenactin-Siderophore Conjugates for Candida: Evidence of Iron Transport-Dependent Species Selectivity

We investigated the inhibitory activity of synthetic isocyanurate-based as well as linear mono- and trihydroxamate siderophore-drug conjugates against Candida spp. The conjugated drug was 13C-desketoneoenactin (DE). The MICs of siderophore-drug conjugates were determined in the absence and presence...

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Detalhes bibliográficos
Main Authors: Bernier, Geneviève, Girijavallabhan, Vinay, Murray, Aaron, Niyaz, Noormohamed, Ding, Pingyu, Miller, Marvin J., Malouin, François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538862/
https://ncbi.nlm.nih.gov/pubmed/15616301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.241-248.2005
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