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The design and synthesis of an antibacterial phenothiazine–siderophore conjugate

Siderophore–antibiotic conjugates consist of an antibiotic covalently linked by a tether to a siderophore. Such conjugates can demonstrate enhanced uptake and internalisation to the bacterial cell resulting in significantly reduced MIC values and extended spectrum of activity. Phenothiazines are a c...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Tarapdar, Abed, Norris, James K S, Sampson, Oliver, Mukamolova, Galina, Hodgkinson, James T
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204836/
https://ncbi.nlm.nih.gov/pubmed/30410626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.242
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