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The design and synthesis of an antibacterial phenothiazine–siderophore conjugate
Siderophore–antibiotic conjugates consist of an antibiotic covalently linked by a tether to a siderophore. Such conjugates can demonstrate enhanced uptake and internalisation to the bacterial cell resulting in significantly reduced MIC values and extended spectrum of activity. Phenothiazines are a c...
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| Опубликовано в: : | Beilstein J Org Chem |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Beilstein-Institut
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204836/ https://ncbi.nlm.nih.gov/pubmed/30410626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.242 |
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