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Molecular diversity of phenothiazines: design and synthesis of phenothiazine–dithiocarbamate hybrids as potential cell cycle blockers

Novel phenothiazine–dithiocarbamate analogues were designed by molecular hybridization strategy and synthesized and evaluated for their anticancer activity in vitro against three selected cancer cell lines (EC-109, MGC-803, and PC-3). The preliminary structure–activity relationship (SAR) for this ph...

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Dades bibliogràfiques
Publicat a:Mol Divers
Autors principals: Fu, Dong-Jun, Zhao, Ruo-Han, Li, Jia-Huan, Yang, Jia-Jia, Mao, Ruo-Wang, Wu, Bo-Wen, Li, Ping, Zi, Xiao-Lin, Zhang, Qing-Qing, Cai, Hui-Jie, Zhang, Sai-Yang, Zhang, Yan-Bing, Liu, Hong-Min
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975273/
https://ncbi.nlm.nih.gov/pubmed/28785928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11030-017-9773-4
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