Molecular diversity of phenothiazines: design and synthesis of phenothiazine–dithiocarbamate hybrids as potential cell cycle blockers

Novel phenothiazine–dithiocarbamate analogues were designed by molecular hybridization strategy and synthesized and evaluated for their anticancer activity in vitro against three selected cancer cell lines (EC-109, MGC-803, and PC-3). The preliminary structure–activity relationship (SAR) for this ph...

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Detalhes bibliográficos
Publicado no:Mol Divers
Main Authors: Fu, Dong-Jun, Zhao, Ruo-Han, Li, Jia-Huan, Yang, Jia-Jia, Mao, Ruo-Wang, Wu, Bo-Wen, Li, Ping, Zi, Xiao-Lin, Zhang, Qing-Qing, Cai, Hui-Jie, Zhang, Sai-Yang, Zhang, Yan-Bing, Liu, Hong-Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975273/
https://ncbi.nlm.nih.gov/pubmed/28785928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11030-017-9773-4
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