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Design and Antiproliferative Evaluation of Novel Sulfanilamide Derivatives as Potential Tubulin Polymerization Inhibitors

A series of sulfanilamide-1,2,3-triazole hybrids were designed by a molecular hybridization strategy and evaluated for antiproliferative activity against three selected cancer cell lines (MGC-803, MCF-7 and PC-3). The detailed structure-activity relationships for these sulfanilamide-1,2,3-triazole h...

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Vydáno v:Molecules
Hlavní autoři: Fu, Dong-Jun, Liu, Ji-Feng, Zhao, Ruo-Han, Li, Jia-Huan, Zhang, Sai-Yang, Zhang, Yan-Bing
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151726/
https://ncbi.nlm.nih.gov/pubmed/28872607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22091470
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