Thiazolidinediones Mimic Glucose Starvation in Facilitating Sp1 Degradation through the Up-Regulation of β-Transducin Repeat-Containing Protein

This study investigated the mechanism by which the transcription factor Sp1 is degraded in prostate cancer cells. We recently developed a thiazolidinedione derivative, (Z)-5-(4-hydroxy-3-trifluoromethylbenzylidene)-3-(1-methylcyclohexyl)-thiazolidine-2,4-dione (OSU-CG12), that induces Sp1 degradatio...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wei, Shuo, Chuang, Hsiao-Ching, Tsai, Wan-Chi, Yang, Hsiao-Ching, Ho, Shiuh-Rong, Paterson, Andrew J., Kulp, Samuel K., Chen, Ching-Shih
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Pharmacology and Experimental Therapeutics 2009
Θέματα:
Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701453/
https://ncbi.nlm.nih.gov/pubmed/19372209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.055376
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