Specific Residues of RUNX2 Are Obligatory for Formation of BMP2-Induced RUNX2-SMAD Complex to Promote Osteoblast Differentiation

BMP2 signaling and RUNX2 regulatory pathways converge for transcriptional control of bone formation in vivo. SMAD proteins are recruited to RUNX2 regulatory complexes via an overlapping nuclear matrix targeting signal/Smad interacting domain sequence (391–432) in Runx2. To establish the contribution...

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書誌詳細
主要な著者: Javed, Amjad, Afzal, Faiza, Bae, Jong-Sup, Gutierrez, Soraya, Zaidi, Kaleem, Pratap, Jitesh, van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
フォーマット: Artigo
言語:Inglês
出版事項: S. Karger AG 2008
主題:
Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701265/
https://ncbi.nlm.nih.gov/pubmed/18728344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151719
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