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Runx2 activity in committed osteoblasts is not essential for embryonic skeletogenesis
Runx2 transcription factor is essential for the development of mineralized tissue, and is required for osteoblast commitment and chondrocyte maturation. Mice with global deletion of Runx2 exhibit complete failure of bone tissue formation, while chondrocyte-specific Runx2-deficient mice lack endochon...
Tallennettuna:
| Julkaisussa: | Connect Tissue Res |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269215/ https://ncbi.nlm.nih.gov/pubmed/25158191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03008207.2014.923873 |
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