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Runx2 activity in committed osteoblasts is not essential for embryonic skeletogenesis

Runx2 transcription factor is essential for the development of mineralized tissue, and is required for osteoblast commitment and chondrocyte maturation. Mice with global deletion of Runx2 exhibit complete failure of bone tissue formation, while chondrocyte-specific Runx2-deficient mice lack endochon...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Connect Tissue Res
Prif Awduron: Adhami, Mitra D., Rashid, Harunur, Chen, Haiyan, Javed, Amjad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269215/
https://ncbi.nlm.nih.gov/pubmed/25158191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03008207.2014.923873
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