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Sp7 and Runx2 Molecular Complex Synergistically Regulate Expression of Target Genes
Runx2 and Sp7 transcription factors are essential for skeletogenesis. Targeted deletion of either gene results in failure of osteoblast differentiation and bone formation. Loss of bone-matrix gene expression is surprisingly similar in Sp7 and Runx2 null mice. The molecular mechanisms responsible for...
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| Publicado no: | Connect Tissue Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269247/ https://ncbi.nlm.nih.gov/pubmed/25158187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03008207.2014.923872 |
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