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Dwarfism in Homozygous Agc1(CreERT) Mice is Associated with Decreased Expression of Aggrecan
Aggrecan (Acan), a large proteoglycan is abundantly expressed in cartilage tissue. Disruption of Acan gene causes dwarfism and perinatal lethality of homozygous mice. Due to sustained expression of Acan in the growth plate and articular cartilage, Agc(Cre) model has been developed for the regulated...
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| Publicado no: | Genesis |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5648336/ https://ncbi.nlm.nih.gov/pubmed/28921880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.23070 |
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