Sp7 and Runx2 Molecular Complex Synergistically Regulate Expression of Target Genes

Runx2 and Sp7 transcription factors are essential for skeletogenesis. Targeted deletion of either gene results in failure of osteoblast differentiation and bone formation. Loss of bone-matrix gene expression is surprisingly similar in Sp7 and Runx2 null mice. The molecular mechanisms responsible for...

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Bibliografiske detaljer
Udgivet i:Connect Tissue Res
Main Authors: Rashid, Harunur, Ma, Changyan, Chen, Haiyan, Wang, Hengbin, Hassan, Mohammad Q., Sinha, Krishna, de Crombrugghe, Benoit, Javed, Amjad
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269247/
https://ncbi.nlm.nih.gov/pubmed/25158187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03008207.2014.923872
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