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Mitochondrial DNA Impairment in NRTIs-Associated Cardiomyopathy

NRTIs are cornerstones of antiretroviral therapy which have significantly improved HIV/AIDS treatment. Side effects from NRTIs exist. A principal toxicity of NRTIs relates to chronic and cumulative NRTI mitochondrial toxicity in various tissues, including heart. Over the last decade, in vitro and in...

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Detalhes bibliográficos
Main Authors: Kohler, James J., Hosseini, Seyed H., Lewis, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701218/
https://ncbi.nlm.nih.gov/pubmed/18393452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx8000219
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