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Chromosomal translocations induced at specified loci in human stem cells

The precise genetic manipulation of stem and precursor cells offers extraordinary potential for the analysis, prevention, and treatment of human malignancies. Chromosomal translocations are hallmarks of several tumor types where they are thought to have arisen in stem or precursor cells. Although ap...

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Bibliografske podrobnosti
Main Authors: Brunet, Erika, Simsek, Deniz, Tomishima, Mark, DeKelver, Russell, Choi, Vivian M., Gregory, Philip, Urnov, Fyodor, Weinstock, David M., Jasin, Maria
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700748/
https://ncbi.nlm.nih.gov/pubmed/19549848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902076106
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