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Chromosomal translocations induced at specified loci in human stem cells

The precise genetic manipulation of stem and precursor cells offers extraordinary potential for the analysis, prevention, and treatment of human malignancies. Chromosomal translocations are hallmarks of several tumor types where they are thought to have arisen in stem or precursor cells. Although ap...

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Detalhes bibliográficos
Main Authors: Brunet, Erika, Simsek, Deniz, Tomishima, Mark, DeKelver, Russell, Choi, Vivian M., Gregory, Philip, Urnov, Fyodor, Weinstock, David M., Jasin, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700748/
https://ncbi.nlm.nih.gov/pubmed/19549848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902076106
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