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Induction of Chromosomal Translocations in Mouse and Human Cells Using Site-Specific Endonucleases
Reciprocal chromosomal translocations are early and essential events in the malignant transformation of several tumor types, yet the precise mechanisms that mediate translocation formation are poorly understood. We review here the development of approaches to induce and recover translocations betwee...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261771/ https://ncbi.nlm.nih.gov/pubmed/18647997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncimonographs/lgn009 |
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