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Induction of site-specific chromosomal translocations in embryonic stem cells by CRISPR/Cas9
Chromosomal translocation is the most common form of chromosomal abnormality and is often associated with congenital genetic disorders, infertility, and cancers. The lack of cellular and animal models for chromosomal translocations, however, has hampered our ability to understand the underlying dise...
Uloženo v:
| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4761995/ https://ncbi.nlm.nih.gov/pubmed/26898344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21918 |
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