Induction of site-specific chromosomal translocations in embryonic stem cells by CRISPR/Cas9

Chromosomal translocation is the most common form of chromosomal abnormality and is often associated with congenital genetic disorders, infertility, and cancers. The lack of cellular and animal models for chromosomal translocations, however, has hampered our ability to understand the underlying dise...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Jiang, Junfeng, Zhang, Li, Zhou, Xingliang, Chen, Xi, Huang, Guanyi, Li, Fengsheng, Wang, Ruizhe, Wu, Nancy, Yan, Youzhen, Tong, Chang, Srivastava, Sankalp, Wang, Yue, Liu, Houqi, Ying, Qi-Long
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761995/
https://ncbi.nlm.nih.gov/pubmed/26898344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21918
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker