Analysis of human α globin gene mutations that impair binding to the α hemoglobin stabilizing protein

Alpha hemoglobin stabilizing protein (AHSP) reversibly binds nascent α globin to maintain its native structure and facilitate its incorporation into hemoglobin A. Previous studies indicate that some naturally occurring human α globin mutations may destabilize the protein by inhibiting its interactio...

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Detaylı Bibliyografya
Asıl Yazarlar: Yu, Xiang, Mollan, Todd L., Butler, Andrew, Gow, Andrew J., Olson, John S., Weiss, Mitchell J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2009
Konular:
Red Cells, Iron, and Erythropoiesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700329/
https://ncbi.nlm.nih.gov/pubmed/19349619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-196030
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