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Analysis of human α globin gene mutations that impair binding to the α hemoglobin stabilizing protein
Alpha hemoglobin stabilizing protein (AHSP) reversibly binds nascent α globin to maintain its native structure and facilitate its incorporation into hemoglobin A. Previous studies indicate that some naturally occurring human α globin mutations may destabilize the protein by inhibiting its interactio...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700329/ https://ncbi.nlm.nih.gov/pubmed/19349619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-196030 |
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