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Probing the mitotic history and developmental stage of hematopoietic cells using single telomere length analysis (STELA)

In most human somatic cells, telomeres shorten as a function of DNA replication. Telomere length is therefore an indirect measure of the replicative history of cells. We measured the telomere lengths at XpYp chromosomes in purified human hematopoietic populations enriched for stem cells (Lin(−)CD34(...

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Detalles Bibliográficos
Main Authors: Hills, Mark, Lücke, Kai, Chavez, Elizabeth A., Eaves, Connie J., Lansdorp, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700317/
https://ncbi.nlm.nih.gov/pubmed/19359409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-198374
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