Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita

Dyskeratosis congenita (DC) is an inherited bone marrow (BM) failure syndrome associated with mutations in telomerase genes and the acquisition of shortened telomeres in blood cells. To investigate the basis of the compromised hematopoiesis seen in DC, we analyzed cells from granulocyte colony-stimu...

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Bibliographic Details
Main Authors: Goldman, Frederick D., Aubert, Geraldine, Klingelhutz, Al J., Hills, Mark, Cooper, Sarah R., Hamilton, Wendy S., Schlueter, Annette J., Lambie, Karen, Eaves, Connie J., Lansdorp, Peter M.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2008
Subjects:
Hematopoiesis and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343591/
https://ncbi.nlm.nih.gov/pubmed/18310499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-120204
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