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DNA Damage Responses and Oxidative Stress in Dyskeratosis Congenita

Dyskeratosis congenita (DC) is an inherited multisystem disorder of premature aging, cancer predisposition, and bone marrow failure caused by selective exhaustion of highly proliferative cell pools. DC patients also have a poor tolerance to chemo/radiotherapy and bone marrow transplantation. Althoug...

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Detalhes bibliográficos
Main Authors: Pereboeva, Larisa, Westin, Erik, Patel, Toral, Flaniken, Ian, Lamb, Lawrence, Klingelhutz, Aloysius, Goldman, Frederick
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790691/
https://ncbi.nlm.nih.gov/pubmed/24124565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076473
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