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Dyskeratosis congenita and the DNA damage response
Dyskeratosis congenita (DC) is a heterogeneous bone marrow failure disorder with known mutations in components of telomerase and telomere shelterin. Recent work in a mouse model with a dyskerin mutation has implicated an increased DNA damage response as part of the cellular pathology, while mouse mo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328754/ https://ncbi.nlm.nih.gov/pubmed/21477209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08679.x |
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