DNA Damage Responses and Oxidative Stress in Dyskeratosis Congenita

Dyskeratosis congenita (DC) is an inherited multisystem disorder of premature aging, cancer predisposition, and bone marrow failure caused by selective exhaustion of highly proliferative cell pools. DC patients also have a poor tolerance to chemo/radiotherapy and bone marrow transplantation. Althoug...

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Bibliographic Details
Main Authors: Pereboeva, Larisa, Westin, Erik, Patel, Toral, Flaniken, Ian, Lamb, Lawrence, Klingelhutz, Aloysius, Goldman, Frederick
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790691/
https://ncbi.nlm.nih.gov/pubmed/24124565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076473
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