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Mechanism of ATP-driven PCNA clamp loading by S. cerevisiae RFC

Circular clamps tether polymerases to DNA, serving as essential processivity factors in genome replication, and function in other critical cellular processes as well. Clamp loaders catalyze clamp assembly onto DNA, and the question of how these proteins construct a topological link between a clamp a...

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Bibliografske podrobnosti
Main Authors: Chen, Siying, Levin, Mikhail K., Sakato, Miho, Zhou, Yayan, Hingorani, Manju M.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700029/
https://ncbi.nlm.nih.gov/pubmed/19285992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.014
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