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Mechanism of ATP-driven PCNA clamp loading by S. cerevisiae RFC

Circular clamps tether polymerases to DNA, serving as essential processivity factors in genome replication, and function in other critical cellular processes as well. Clamp loaders catalyze clamp assembly onto DNA, and the question of how these proteins construct a topological link between a clamp a...

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Autors principals: Chen, Siying, Levin, Mikhail K., Sakato, Miho, Zhou, Yayan, Hingorani, Manju M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700029/
https://ncbi.nlm.nih.gov/pubmed/19285992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.014
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