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Rapid Identification of Enzyme Variants for Reengineered Alkaloid Biosynthesis in Periwinkle

Monoterpene indole alkaloids from Catharanthus roseus (Madagascar periwinkle), such as the anticancer agents vinblastine and vincristine, have important pharmacological activities. Metabolic engineering of alkaloid biosynthesis can provide an efficient and environmentally friendly route to analogs o...

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書誌詳細
主要な著者: Bernhardt, Peter, McCoy, Elizabeth, O’Connor, Sarah E.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700010/
https://ncbi.nlm.nih.gov/pubmed/17719488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2007.07.008
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