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Rapid Identification of Enzyme Variants for Reengineered Alkaloid Biosynthesis in Periwinkle
Monoterpene indole alkaloids from Catharanthus roseus (Madagascar periwinkle), such as the anticancer agents vinblastine and vincristine, have important pharmacological activities. Metabolic engineering of alkaloid biosynthesis can provide an efficient and environmentally friendly route to analogs o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700010/ https://ncbi.nlm.nih.gov/pubmed/17719488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2007.07.008 |
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