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Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak

Bak and Bax are critical apoptotic mediators that naturally localize to both mitochondria and the endoplasmic reticulum (ER). Although it is generally accepted that mitochondrial expression of Bak or Bax suffices for apoptosis initiated by BH3-only homologues, it is currently unclear whether their r...

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Hlavní autoři: Klee, Martina, Pallauf, Kathrin, Alcalá, Sonia, Fleischer, Aarne, Pimentel-Muiños, Felipe X
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699367/
https://ncbi.nlm.nih.gov/pubmed/19339988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.90
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