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TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3

Selective autophagy underlies many of the important physiological roles that autophagy plays in multicellular organisms, but the mechanisms involved in cargo selection are poorly understood. Here we describe a molecular mechanism that can target conventional endosomes for autophagic degradation. We...

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Detalhes bibliográficos
Main Authors: Boada-Romero, Emilio, Letek, Michal, Fleischer, Aarne, Pallauf, Kathrin, Ramón-Barros, Cristina, Pimentel-Muiños, Felipe X
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579146/
https://ncbi.nlm.nih.gov/pubmed/23376921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.8
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