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TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3
Selective autophagy underlies many of the important physiological roles that autophagy plays in multicellular organisms, but the mechanisms involved in cargo selection are poorly understood. Here we describe a molecular mechanism that can target conventional endosomes for autophagic degradation. We...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
European Molecular Biology Organization
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3579146/ https://ncbi.nlm.nih.gov/pubmed/23376921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.8 |
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