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Bcl-X(L) specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum
Bcl-2 family members Bak and Bax constitute a mitochondrial gateway for multiple death pathways. Both proteins are also present in the endoplasmic reticulum where they control apoptosis through the regulation of calcium levels. We show here that reticular Bak has the additional capacity of modulatin...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171806/ https://ncbi.nlm.nih.gov/pubmed/15728194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200408169 |
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