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The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP(3)R
Members of the Bcl-2 protein family modulate outer mitochondrial membrane permeability to control apoptosis1,2. However, these proteins also localize to the endoplasmic reticulum (ER), the functional significance of which is controversial3, 4. Here we provide evidence that anti-apoptotic Bcl-2 prote...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893337/ https://ncbi.nlm.nih.gov/pubmed/16179951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1302 |
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