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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

Bax and Bak play a redundant but essential role in apoptosis initiated by the mitochondrial release of apoptogenic factors. In addition to their presence at the mitochondrial outer membrane, Bax and Bak can also localize to the ER. Agents that initiate ER stress responses can induce conformational c...

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Podrobná bibliografie
Hlavní autoři: Zong, Wei-Xing, Li, Chi, Hatzivassiliou, Georgia, Lindsten, Tullia, Yu, Qian-Chun, Yuan, Junying, Thompson, Craig B.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172724/
https://ncbi.nlm.nih.gov/pubmed/12847083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302084
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