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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

Bax and Bak play a redundant but essential role in apoptosis initiated by the mitochondrial release of apoptogenic factors. In addition to their presence at the mitochondrial outer membrane, Bax and Bak can also localize to the ER. Agents that initiate ER stress responses can induce conformational c...

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Dettagli Bibliografici
Autori principali: Zong, Wei-Xing, Li, Chi, Hatzivassiliou, Georgia, Lindsten, Tullia, Yu, Qian-Chun, Yuan, Junying, Thompson, Craig B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172724/
https://ncbi.nlm.nih.gov/pubmed/12847083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302084
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