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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
Bax and Bak play a redundant but essential role in apoptosis initiated by the mitochondrial release of apoptogenic factors. In addition to their presence at the mitochondrial outer membrane, Bax and Bak can also localize to the ER. Agents that initiate ER stress responses can induce conformational c...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172724/ https://ncbi.nlm.nih.gov/pubmed/12847083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302084 |
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