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Bcl-X(L) specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum
Bcl-2 family members Bak and Bax constitute a mitochondrial gateway for multiple death pathways. Both proteins are also present in the endoplasmic reticulum where they control apoptosis through the regulation of calcium levels. We show here that reticular Bak has the additional capacity of modulatin...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171806/ https://ncbi.nlm.nih.gov/pubmed/15728194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200408169 |
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