טוען...
Indoleamine 2,3-dioxygenase controls conversion of Foxp3(+) Tregs to TH17-like cells in tumor-draining lymph nodes
The immunoregulatory enzyme indoleamine 2,3-dioxygenase (IDO) is expressed by a subset of murine plasmacytoid DCs (pDCs) in tumor-draining lymph nodes (TDLNs), where it can potently activate Foxp3(+) regulatory T cells (Tregs). We now show that IDO functions as a molecular switch in TDLNs, maintaini...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699232/ https://ncbi.nlm.nih.gov/pubmed/19366986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-195354 |
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