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Indoleamine 2,3-dioxygenase and tumor-induced tolerance

Tumors arise from normal cells of the body through genetic mutation. Although such genetic mutation often leads to the expression of abnormal antigens, the immune system fails to respond effectively to these antigens; that is, it is tolerant of these antigens. This acquired state of tolerance must b...

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Bibliografiska uppgifter
Huvudupphovsmän: Munn, David H., Mellor, Andrew L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857253/
https://ncbi.nlm.nih.gov/pubmed/17476344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31178
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