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Indoleamine 2,3-dioxygenase and tumor-induced tolerance

Tumors arise from normal cells of the body through genetic mutation. Although such genetic mutation often leads to the expression of abnormal antigens, the immune system fails to respond effectively to these antigens; that is, it is tolerant of these antigens. This acquired state of tolerance must b...

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Detalles Bibliográficos
Autores principales: Munn, David H., Mellor, Andrew L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2007
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857253/
https://ncbi.nlm.nih.gov/pubmed/17476344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31178
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