Ubiquitin-Regulated Recruitment of IκB Kinase ɛ to the MAVS Interferon Signaling Adapter

Induction of the antiviral interferon response is initiated upon recognition of viral RNA structures by the RIG-I or Mda-5 DEX(D/H) helicases. A complex signaling cascade then converges at the mitochondrial adapter MAVS, culminating in the activation of the IRF and NF-κB transcription factors and th...

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Autores principales: Paz, Suzanne, Vilasco, Myriam, Arguello, Meztli, Sun, Qiang, Lacoste, Judith, Nguyen, Thi Lien-Anh, Zhao, Tiejun, Shestakova, Elena A., Zaari, Scott, Bibeau-Poirier, Annie, Servant, Marc J., Lin, Rongtuan, Meurs, Eliane F., Hiscott, John
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698723/
https://ncbi.nlm.nih.gov/pubmed/19380491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00880-08
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