A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response

Recognition of viral RNA structures by the cytosolic sensor retinoic acid-inducible gene-I (RIG-I) results in the activation of signaling cascades that culminate with the generation of the type I interferon (IFN) antiviral response. Onset of antiviral and inflammatory responses to viral pathogens ne...

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Detalhes bibliográficos
Main Authors: Paz, Suzanne, Vilasco, Myriam, Werden, Steven J, Arguello, Meztli, Joseph-Pillai, Deshanthe, Zhao, Tiejun, Nguyen, Thi Lien-Anh, Sun, Qiang, Meurs, Eliane F, Lin, Rongtuan, Hiscott, John
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203699/
https://ncbi.nlm.nih.gov/pubmed/21200404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.2
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