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Lnk inhibits myeloproliferative disorder-associated JAK2 mutant, JAK2V617F
The JAK2 mutation JAK2V617F is found frequently in patients with myeloproliferative disorders (MPD) and transforms hematopoietic cells to cytokine-independent proliferation when expressed with specific cytokine receptors. The Src homology 2 (SH2) and pleckstrin homology (PH) domain-containing adapto...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Society for Leukocyte Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698587/ https://ncbi.nlm.nih.gov/pubmed/19293402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0908575 |
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