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STAT5 Activation Is Critical for the Transformation Mediated by Myeloproliferative Disorder-associated JAK2 V617F Mutant

It has been well established that disruption of JAK2 signaling regulation is involved in various hematopoietic disorders; however, the detailed mechanism by which abnormal activation of JAK2 exhibits transforming activity remains to be elucidated. Here, to clarify the functional role of the erythrop...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Funakoshi-Tago, Megumi, Tago, Kenji, Abe, Miyuki, Sonoda, Yoshiko, Kasahara, Tadashi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820758/
https://ncbi.nlm.nih.gov/pubmed/20028972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.040733
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