Coffee reduces KRAS expression in Caco-2 human colon carcinoma cells via regulation of miRNAs

by Nakayama, Takuya, Funakoshi-Tago, Megumi, Tamura, Hiroomi
Published in Oncol Lett (2017)

Critical Roles of Myc-ODC Axis in the Cellular Transformation Induced by Myeloproliferative Neoplasm-Associated JAK2 V617F Mutant

by Funakoshi-Tago, Megumi, Sumi, Kazuya, Kasahara, Tadashi, Tago, Kenji
Published 2013

Three Tyrosine Residues in the Erythropoietin Receptor Are Essential for Janus Kinase 2 V617F Mutant-induced Tumorigenesis

by Ueda, Fumihito, Tago, Kenji, Tamura, Hiroomi, Funakoshi-Tago, Megumi
Published in J Biol Chem (2017)

EBP2, a novel NPM‐ALK‐interacting protein in the nucleolus, contributes to the proliferation of ALCL cells by regulating tumor suppressor p53

by Uchihara, Yuki, Tago, Kenji, Tamura, Hiroomi, Funakoshi‐Tago, Megumi
Published in Mol Oncol (2020)

STAT5 Activation Is Critical for the Transformation Mediated by Myeloproliferative Disorder-associated JAK2 V617F Mutant

by Funakoshi-Tago, Megumi, Tago, Kenji, Abe, Miyuki, Sonoda, Yoshiko, Kasahara, Tadashi
Published 2010

κB-Ras Is a Nuclear-Cytoplasmic Small GTPase That Inhibits NF-κB Activation through the Suppression of Transcriptional Activation of p65/RelA

by Tago, Kenji, Funakoshi-Tago, Megumi, Sakinawa, Masaki, Mizuno, Norikazu, Itoh, Hiroshi
Published 2010

Dynamin Isoforms Decode Action Potential Firing for Synaptic Vesicle Recycling

by Tanifuji, Shota, Funakoshi-Tago, Megumi, Ueda, Fumihito, Kasahara, Tadashi, Mochida, Sumiko
Published 2013

Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation

by Funakoshi-Tago, Megumi, Yu, Seisho, Kushida, Akira, Takeuchi, Kazusane, Tamura, Hiroomi
Published in Heliyon (2020)

Coffee decoction enhances tamoxifen proapoptotic activity on MCF-7 cells

by Funakoshi-Tago, Megumi, Tago, Kenji, Li, Chin, Hokimoto, Shingo, Tamura, Hiroomi
Published in Sci Rep (2020)

Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2

by Funakoshi-Tago, Megumi, Pelletier, Stephane, Matsuda, Tadashi, Parganas, Evan, Ihle, James N
Published 2006

Two Domains of the Erythropoietin Receptor Are Sufficient for Jak2 Binding/Activation and Function

by Pelletier, Stéphane, Gingras, Sébastien, Funakoshi-Tago, Megumi, Howell, Sherié, Ihle, James N.
Published 2006

Jak2 FERM Domain Interaction with the Erythropoietin Receptor Regulates Jak2 Kinase Activity

by Funakoshi-Tago, Megumi, Pelletier, Stéphane, Moritake, Hiroshi, Parganas, Evan, Ihle, James N.
Published 2008

Knockdown of proteolipid protein 2 or focal adhesion kinase with an artificial microRNA reduces growth and metastasis of B16BL6 melanoma cells

by OZAWA, HIROKI, SONODA, YOSHIKO, SUZUKI, TAKAHARU, YOSHIDA-HOSHINA, NAOMI, FUNAKOSHI-TAGO, MEGUMI, KASAHARA, TADASHI
Published 2012

A proline-type fullerene derivative inhibits adipogenesis by preventing PPARγ activation

by Funakoshi-Tago, Megumi, Hattori, Takahiro, Ueda, Fumihito, Tago, Kenji, Ohe, Tomoyuki, Mashino, Tadahiko, Tamura, Hiroomi
Published in Biochem Biophys Rep (2016)

Coffee brew intake can prevent the reduction of lens glutathione and ascorbic acid levels in HFD-fed animals

by Nakazawa, Yosuke, Ishimori, Nana, Oguchi, Jun, Nagai, Noriaki, Kimura, Masaki, Funakoshi-Tago, Megumi, Tamura, Hiroomi
Published in Exp Ther Med (2019)

ST2 gene products critically contribute to cellular transformation caused by an oncogenic Ras mutant

by Tago, Kenji, Ohta, Satoshi, Kashiwada, Masaki, Funakoshi-Tago, Megumi, Matsugi, Jitsuhiro, Tominaga, Shin-ichi, Yanagisawa, Ken
Published in Heliyon (2017)

STAT3 and ERK pathways are involved in cell growth stimulation of the ST2/IL1RL1 promoter

by Tago, Kenji, Ohta, Satoshi, Funakoshi‐Tago, Megumi, Aoki‐Ohmura, Chihiro, Matsugi, Jitsuhiro, Tominaga, Shin‐ichi, Yanagisawa, Ken
Published in FEBS Open Bio (2017)

Coffee extract inhibits adipogenesis in 3T3-L1 preadipocyes by interrupting insulin signaling through the downregulation of IRS1

by Maki, Chihiro, Funakoshi-Tago, Megumi, Aoyagi, Ryohei, Ueda, Fumihito, Kimura, Masaki, Kobata, Kenji, Tago, Kenji, Tamura, Hiroomi
Published in PLoS One (2017)

Oral consumption of α-glucosyl-hesperidin could prevent lens hardening, which causes presbyopia

by Nakazawa, Yosuke, Aoki, Miki, Doki, Yuri, Morishita, Naoki, Endo, Shin, Nagai, Noriaki, Funakoshi-Tago, Megumi, Tamura, Hiroomi
Published in Biochem Biophys Rep (2020)

The Acute Lymphoblastic Leukemia-associated JAK2 L611S Mutant Induces Tumorigenesis in Nude Mice

by Funakoshi-Tago, Megumi, Tago, Kenji, Sumi, Kazuya, Abe, Miyuki, Aizu-Yokota, Eriko, Oshio, Tomoyuki, Sonoda, Yoshiko, Kasahara, Tadashi
Published 2009