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κB-Ras Is a Nuclear-Cytoplasmic Small GTPase That Inhibits NF-κB Activation through the Suppression of Transcriptional Activation of p65/RelA

NF-κB is an important transcription factor involved in various biological responses, including inflammation, cell differentiation, and tumorigenesis. κB-Ras was identified as an IκB-interacting small GTPase and is reported to disturb cytokine-induced NF-κB activation. In this study, we established t...

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Autors principals: Tago, Kenji, Funakoshi-Tago, Megumi, Sakinawa, Masaki, Mizuno, Norikazu, Itoh, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945557/
https://ncbi.nlm.nih.gov/pubmed/20639196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.117028
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