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Modeling Subgenomic Hepatitis C Virus RNA Kinetics during Treatment with Alpha Interferon
Although replicons have been used to demonstrate hepatitis C virus (HCV) inhibition by alpha interferon (IFN-α), the detailed inhibition kinetics required to mathematically model HCV RNA decline have been lacking. Therefore, we measured genotype 1b subgenomic replicon (sg1b) RNA levels under various...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698578/ https://ncbi.nlm.nih.gov/pubmed/19369346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02612-08 |
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