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Hepatitis C Virus Subgenomic Replicon Requires an Active NS3 RNA Helicase
Mutations were introduced into the NS3 helicase region of a hepatitis C virus (HCV) Con1 subgenomic replicon to ascertain the role of the helicase in viral replication. One new replicon lacked two-thirds of the NS3 helicase (Δhel), and six others contained one of the following six amino acid substit...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1317551/ https://ncbi.nlm.nih.gov/pubmed/16352565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.1.404-411.2006 |
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