Mathematical Modeling of Subgenomic Hepatitis C Virus Replication in Huh-7 Cells

Cell-based hepatitis C virus (HCV) replicon systems have provided a means for understanding HCV replication mechanisms and for testing new antiviral agents. We describe here a mathematical model of HCV replication that assumes that the translation of the HCV polyprotein occurs in the cytoplasm, that...

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Hlavní autoři: Dahari, Harel, Ribeiro, Ruy M., Rice, Charles M., Perelson, Alan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797446/
https://ncbi.nlm.nih.gov/pubmed/17035310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01304-06
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