Modeling Subgenomic Hepatitis C Virus RNA Kinetics during Treatment with Alpha Interferon

Although replicons have been used to demonstrate hepatitis C virus (HCV) inhibition by alpha interferon (IFN-α), the detailed inhibition kinetics required to mathematically model HCV RNA decline have been lacking. Therefore, we measured genotype 1b subgenomic replicon (sg1b) RNA levels under various...

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Detaylı Bibliyografya
Asıl Yazarlar: Dahari, Harel, Sainz, Bruno, Perelson, Alan S., Uprichard, Susan L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Genome Replication and Regulation of Viral Gene Expression
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698578/
https://ncbi.nlm.nih.gov/pubmed/19369346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02612-08
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