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Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition
Recent studies have identified development of resistance to tyrosine kinase inhibition (TKI) as a significant roadblock to effective treatment. One mechanism of resistance recently appreciated involves ‘oncogene switching’, or the re-activation of signaling pathways by one or more redundant upstream...
Shranjeno v:
| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698221/ https://ncbi.nlm.nih.gov/pubmed/18769157 |
| Oznake: |
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