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Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition

Recent studies have identified development of resistance to tyrosine kinase inhibition (TKI) as a significant roadblock to effective treatment. One mechanism of resistance recently appreciated involves ‘oncogene switching’, or the re-activation of signaling pathways by one or more redundant upstream...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Pashtan, Itai, Tsutsumi, Shinji, Wang, Suiquan, Xu, Wanping, Neckers, Len
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698221/
https://ncbi.nlm.nih.gov/pubmed/18769157
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