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Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome

Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant or spontaneous disorder characterized by multiple cutaneous basal cell carcinomas, odontogenic keratocysts, skeletal anomalies and facial dysmorphology, including cleft lip and palate. Causative mutations for NBCCS occur in the PT...

詳細記述

保存先:
書誌詳細
主要な著者: Cobourne, Martyn T., Xavier, Guilherme M., Depew, Michael, Hagan, Louise, Sealby, Jane, Webster, Zoe, Sharpe, Paul T.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696601/
https://ncbi.nlm.nih.gov/pubmed/19394325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.04.021
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